Partitioning with 1000G LD scores on HapMap3 SNPs with Human_Striatum_snATAC.Microglia.hg38 bed regions
making annot file
Computing partitioned LD scores for hg38 for EUR.
*********************************************************************
* LD Score Regression (LDSC)
* Version 1.0.1
* (C) 2014-2019 Brendan Bulik-Sullivan and Hilary Finucane
* Broad Institute of MIT and Harvard / MIT Department of Mathematics
* GNU General Public License v3
*********************************************************************
Call: 
./ldsc.py \
--print-snps /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt \
--out /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Microglia.hg38.EUR.22 \
--bfile /tmp/ldsc-2024-06-24-z39TjBN1HU/1000G.EUR.HM3.22 \
--thin-annot  \
--annot /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Microglia.hg38.EUR.22.annot.gz \
--l2  \
--ld-wind-kb 1000.0 

Beginning analysis at Mon Jun 24 13:08:24 2024
Read list of 17663 SNPs from /tmp/ldsc-2024-06-24-z39TjBN1HU/1000G.EUR.HM3.22.bim
Read 1 annotations for 17663 SNPs from /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Microglia.hg38.EUR.22.annot.gz
Read list of 503 individuals from /tmp/ldsc-2024-06-24-z39TjBN1HU/1000G.EUR.HM3.22.fam
Reading genotypes from /tmp/ldsc-2024-06-24-z39TjBN1HU/1000G.EUR.HM3.22.bed
After filtering, 17663 SNPs remain
Estimating LD Score.
Reading list of 1215001 SNPs for which to print LD Scores from /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt
After merging with --print-snps, LD Scores for 17663 SNPs will be printed.
Writing LD Scores for 17663 SNPs to /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Microglia.hg38.EUR.22.l2.ldscore.gz

Summary of LD Scores in /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Microglia.hg38.EUR.22.l2.ldscore.gz
         MAF      L2
mean  0.2345  0.4884
std   0.1446  1.0017
min   0.0020 -0.0622
25%   0.1064  0.0052
50%   0.2256  0.0636
75%   0.3569  0.5538
max   0.5000  8.4005

MAF/LD Score Correlation Matrix
       MAF     L2
MAF  1.000  0.141
L2   0.141  1.000

Annotation Correlation Matrix
       ANNOT
ANNOT    1.0

Annotation Matrix Column Sums
ANNOT    448

Summary of Annotation Matrix Row Sums
count    17663.0000
mean         0.0254
std          0.1572
min          0.0000
25%          0.0000
50%          0.0000
75%          0.0000
max          1.0000
Analysis finished at Mon Jun 24 13:09:14 2024
Total time elapsed: 49.59s
Done.