Partitioning with 1000G LD scores on HapMap3 SNPs with Human_Striatum_snATAC.D2.Striosome.hg38 bed regions
making annot file
Computing partitioned LD scores for hg38 for EUR.
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* LD Score Regression (LDSC)
* Version 1.0.1
* (C) 2014-2019 Brendan Bulik-Sullivan and Hilary Finucane
* Broad Institute of MIT and Harvard / MIT Department of Mathematics
* GNU General Public License v3
*********************************************************************
Call: 
./ldsc.py \
--print-snps /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt \
--out /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D2.Striosome.hg38.EUR.18 \
--bfile /tmp/ldsc-2024-06-24-HRatTKwTuI/1000G.EUR.HM3.18 \
--thin-annot  \
--annot /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D2.Striosome.hg38.EUR.18.annot.gz \
--l2  \
--ld-wind-kb 1000.0 

Beginning analysis at Mon Jun 24 13:06:44 2024
Read list of 35783 SNPs from /tmp/ldsc-2024-06-24-HRatTKwTuI/1000G.EUR.HM3.18.bim
Read 1 annotations for 35783 SNPs from /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D2.Striosome.hg38.EUR.18.annot.gz
Read list of 503 individuals from /tmp/ldsc-2024-06-24-HRatTKwTuI/1000G.EUR.HM3.18.fam
Reading genotypes from /tmp/ldsc-2024-06-24-HRatTKwTuI/1000G.EUR.HM3.18.bed
After filtering, 35783 SNPs remain
Estimating LD Score.
Reading list of 1215001 SNPs for which to print LD Scores from /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt
After merging with --print-snps, LD Scores for 35783 SNPs will be printed.
Writing LD Scores for 35783 SNPs to /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D2.Striosome.hg38.EUR.18.l2.ldscore.gz

Summary of LD Scores in /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D2.Striosome.hg38.EUR.18.l2.ldscore.gz
         MAF       L2
mean  0.2349   0.6485
std   0.1431   1.0276
min   0.0020  -0.0773
25%   0.1093   0.0441
50%   0.2237   0.2261
75%   0.3559   0.8779
max   0.5000  11.3092

MAF/LD Score Correlation Matrix
        MAF      L2
MAF  1.0000  0.1064
L2   0.1064  1.0000

Annotation Correlation Matrix
       ANNOT
ANNOT    1.0

Annotation Matrix Column Sums
ANNOT    1371

Summary of Annotation Matrix Row Sums
count    35783.0000
mean         0.0383
std          0.1920
min          0.0000
25%          0.0000
50%          0.0000
75%          0.0000
max          1.0000
Analysis finished at Mon Jun 24 13:08:26 2024
Total time elapsed: 1.0m:42.11s
Done.