Partitioning with 1000G LD scores on HapMap3 SNPs with Human_Striatum_snATAC.D1.Matrix.hg38 bed regions
making annot file
Computing partitioned LD scores for hg38 for EUR.
*********************************************************************
* LD Score Regression (LDSC)
* Version 1.0.1
* (C) 2014-2019 Brendan Bulik-Sullivan and Hilary Finucane
* Broad Institute of MIT and Harvard / MIT Department of Mathematics
* GNU General Public License v3
*********************************************************************
Call: 
./ldsc.py \
--print-snps /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt \
--out /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.EUR.14 \
--bfile /tmp/ldsc-2024-06-24-3oLnt65SFO/1000G.EUR.HM3.14 \
--thin-annot  \
--annot /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.EUR.14.annot.gz \
--l2  \
--ld-wind-kb 1000.0 

Beginning analysis at Mon Jun 24 13:03:48 2024
Read list of 39834 SNPs from /tmp/ldsc-2024-06-24-3oLnt65SFO/1000G.EUR.HM3.14.bim
Read 1 annotations for 39834 SNPs from /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.EUR.14.annot.gz
Read list of 503 individuals from /tmp/ldsc-2024-06-24-3oLnt65SFO/1000G.EUR.HM3.14.fam
Reading genotypes from /tmp/ldsc-2024-06-24-3oLnt65SFO/1000G.EUR.HM3.14.bed
After filtering, 39834 SNPs remain
Estimating LD Score.
Reading list of 1215001 SNPs for which to print LD Scores from /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt
After merging with --print-snps, LD Scores for 39834 SNPs will be printed.
Writing LD Scores for 39834 SNPs to /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.EUR.14.l2.ldscore.gz

Summary of LD Scores in /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.EUR.14.l2.ldscore.gz
         MAF       L2
mean  0.2305   1.1457
std   0.1432   1.7710
min   0.0020  -0.1283
25%   0.1054   0.1193
50%   0.2177   0.4512
75%   0.3499   1.3710
max   0.5000  13.4776

MAF/LD Score Correlation Matrix
        MAF      L2
MAF  1.0000  0.1127
L2   0.1127  1.0000

Annotation Correlation Matrix
       ANNOT
ANNOT    1.0

Annotation Matrix Column Sums
ANNOT    2270

Summary of Annotation Matrix Row Sums
count    39834.0000
mean         0.0570
std          0.2318
min          0.0000
25%          0.0000
50%          0.0000
75%          0.0000
max          1.0000
Analysis finished at Mon Jun 24 13:05:55 2024
Total time elapsed: 2.0m:6.95s
Done.