Partitioning with 1000G LD scores on HapMap3 SNPs with Human_Striatum_snATAC.D1.Matrix.hg38 bed regions
making annot file
Computing partitioned LD scores for hg38 for AFR.
*********************************************************************
* LD Score Regression (LDSC)
* Version 1.0.1
* (C) 2014-2019 Brendan Bulik-Sullivan and Hilary Finucane
* Broad Institute of MIT and Harvard / MIT Department of Mathematics
* GNU General Public License v3
*********************************************************************
Call: 
./ldsc.py \
--print-snps /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt \
--out /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.AFR.22 \
--bfile /tmp/ldsc-2024-06-24-t4bvBwFdrK/1000G.AFR.HM3.22 \
--thin-annot  \
--annot /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.AFR.22.annot.gz \
--l2  \
--ld-wind-kb 1000.0 

Beginning analysis at Mon Jun 24 13:03:48 2024
Read list of 17585 SNPs from /tmp/ldsc-2024-06-24-t4bvBwFdrK/1000G.AFR.HM3.22.bim
Read 1 annotations for 17585 SNPs from /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.AFR.22.annot.gz
Read list of 661 individuals from /tmp/ldsc-2024-06-24-t4bvBwFdrK/1000G.AFR.HM3.22.fam
Reading genotypes from /tmp/ldsc-2024-06-24-t4bvBwFdrK/1000G.AFR.HM3.22.bed
After filtering, 17585 SNPs remain
Estimating LD Score.
Reading list of 1215001 SNPs for which to print LD Scores from /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt
After merging with --print-snps, LD Scores for 17585 SNPs will be printed.
Writing LD Scores for 17585 SNPs to /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.AFR.22.l2.ldscore.gz

Summary of LD Scores in /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.D1.Matrix.hg38.AFR.22.l2.ldscore.gz
         MAF       L2
mean  0.2165   0.7642
std   0.1478   1.3012
min   0.0015  -0.0655
25%   0.0855   0.0895
50%   0.2012   0.3066
75%   0.3404   0.9546
max   0.5000  13.2576

MAF/LD Score Correlation Matrix
       MAF     L2
MAF  1.000  0.073
L2   0.073  1.000

Annotation Correlation Matrix
       ANNOT
ANNOT    1.0

Annotation Matrix Column Sums
ANNOT    1181

Summary of Annotation Matrix Row Sums
count    17585.0000
mean         0.0672
std          0.2503
min          0.0000
25%          0.0000
50%          0.0000
75%          0.0000
max          1.0000
Analysis finished at Mon Jun 24 13:04:47 2024
Total time elapsed: 59.0s
Done.