Partitioning with 1000G LD scores on HapMap3 SNPs with Human_Striatum_snATAC.Astro.hg38 bed regions
making annot file
Computing partitioned LD scores for hg38 for AFR.
*********************************************************************
* LD Score Regression (LDSC)
* Version 1.0.1
* (C) 2014-2019 Brendan Bulik-Sullivan and Hilary Finucane
* Broad Institute of MIT and Harvard / MIT Department of Mathematics
* GNU General Public License v3
*********************************************************************
Call: 
./ldsc.py \
--print-snps /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt \
--out /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Astro.hg38.AFR.1 \
--bfile /tmp/ldsc-2024-06-24-BoA0ltMWEw/1000G.AFR.HM3.1 \
--thin-annot  \
--annot /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Astro.hg38.AFR.1.annot.gz \
--l2  \
--ld-wind-kb 1000.0 

Beginning analysis at Mon Jun 24 13:03:48 2024
Read list of 98866 SNPs from /tmp/ldsc-2024-06-24-BoA0ltMWEw/1000G.AFR.HM3.1.bim
Read 1 annotations for 98866 SNPs from /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Astro.hg38.AFR.1.annot.gz
Read list of 661 individuals from /tmp/ldsc-2024-06-24-BoA0ltMWEw/1000G.AFR.HM3.1.fam
Reading genotypes from /tmp/ldsc-2024-06-24-BoA0ltMWEw/1000G.AFR.HM3.1.bed
After filtering, 98866 SNPs remain
Estimating LD Score.
Reading list of 1215001 SNPs for which to print LD Scores from /projects/pfenninggroup/machineLearningForComputationalBiology/gwasEnrichments/1000G_EUR_Phase3_GRCh38_files/hapmap3_snps/listHM3.noMHC.txt
After merging with --print-snps, LD Scores for 98866 SNPs will be printed.
Writing LD Scores for 98866 SNPs to /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Astro.hg38.AFR.1.l2.ldscore.gz

Summary of LD Scores in /projects/pfenninggroup/machineLearningForComputationalBiology/StriatumComparativeGenomics/data/tidy_data/human_Str_ldsc/annotations/Human_Striatum_snATAC.Astro.hg38.AFR.1.l2.ldscore.gz
         MAF      L2
mean  0.2223  0.3629
std   0.1459  0.6035
min   0.0015 -0.0519
25%   0.0953  0.0343
50%   0.2110  0.1200
75%   0.3427  0.4015
max   0.5000  7.4793

MAF/LD Score Correlation Matrix
        MAF      L2
MAF  1.0000  0.0669
L2   0.0669  1.0000

Annotation Correlation Matrix
       ANNOT
ANNOT    1.0

Annotation Matrix Column Sums
ANNOT    3312

Summary of Annotation Matrix Row Sums
count    98866.0000
mean         0.0335
std          0.1799
min          0.0000
25%          0.0000
50%          0.0000
75%          0.0000
max          1.0000
Analysis finished at Mon Jun 24 13:18:01 2024
Total time elapsed: 14.0m:13.16s
Done.